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Chemistry of Fried Beef Liver: Good? Bad? Yucky?

December 15, 2016 by Vincent Summers 5 Comments

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Delicious eating for some: Fried Beef Liver. Image courtesy of Lani Cooks, all rights reserved, used with permission.

“And in this corner…” so starts the boxing match.

What does that have to do with liver?

It illustrates people’s feelings concerning fried liver. They either love it or they hate it.

What’s the chemistry of liver – and how does it impact your health? For liver to have any effect at all, you have to actually take a bite – so let’s first consider some of the typical statements people make about this food. Those people who stick up their nose at the mere mention of fried beef liver.

Those Who Stick Up Their Nose

You are doubtless aware of what the raised nose signifies. It suggests snobbery – the feeling, in some context, of superiority of one over another.

The non-liver-eater may feel more sophisticated and health-conscious than the one who eats liver. You may have heard (or said):

  • Liver is “yucky” (or something similar)
  • Liver filters toxins from the blood – who wants to eat toxins?
  • Liver is high in fat and cholesterol – that’s bad for you!

When I’ve heard “yucky” in connection with liver, it usually means that it looks “yucky” or smells “yucky” when cooking – the same has been said of other foods, even popular ones such as lamb or tongue. The complainer may not even be referring to taste, and may have never even tried fried beef liver. If he did taste it, it probably was only as a child when “Clean your plate!” was still a rule.

As to the filtering of toxins, yes, it’s true. The human liver, for instance, filters toxins. In fact, the liver converts fat-soluble toxins into water-soluble substances that are readily disposed of in the urine. Some of these substances are referenced in the cited Cornell College reference. Among them are “medications, drugs, hormone enhancers, food additives, preservatives, food colorings, sweeteners, flavor enhancers, chemicals used in agriculture, alcohols, volatile organic compounds, fumes, air pollution.”

  The third complaint is that liver is high in fat and cholesterol. We’ll obtain a clearer understanding on that issue below. First, let us cook the liver we’re going to eat.

How Fried Beef Liver is Prepared

Store-bought liver is de-veined and usually sliced. The home cook then washes, flours, and fries the liver, often in a cast iron pan, frequently nestled in onions. Perhaps a bit of bacon or some other “secret ingredient” is added as well. The dish is fried until deeply caramelized. Caramelization refers to cooking a food item until the sugar molecules in it form caramel.

Admittedly some liver is better than others. It’s important to find a quality source and purchase that, as with any other food product. As to variety, there is beef or calves liver. There is also pork, chicken, and deer liver—in fact there are many others as well. We will consider beef liver in this article.

Chemically-Speaking, What is in Liver—Good and Bad?

Chemically-speaking, there’s a lot going on in liver: protein, spermine, vitamins and minerals.

Liver contains a little over 20% protein, one of the most important dietary ingredients.

Proteins consist of amino acids joined together (with loss of water) to form peptide linkages.Peptide linkages are linkages of the form -CO-NH- as shown in the diagram.

Amino acids join by means of peptide linkages to form proteins. Copyright image by Vincent Summers, all rights reserved.

Protein is also rich in nitrogen, an important constituent of DNA and RNA.

One nitrogen-rich dietary nutrient especially abundant in beef liver is spermine. Curiously, researchers believe spermine serves as a free-radical scavenging protector of DNA. A free radical is a molecular fragment that contains a free, that is an unbound, electron.

Spermine is a nitrogen rich free-radical scavenger that protects DNA. Image by Calvero (modified).

In addition, liver is rich in all the B vitamins, some trace metals, and folic acid. Add to this glowing report that liver is iron-rich. A small serving of liver provides twice the daily requirement of iron.

Liver is very rich in Vitamin A as well. In fact, it is so rich in “A” that it is wise to minimize a serving to a handful of ounces.

The author has eaten as much as a pound of fried beef liver. That quantity of liver contains about 3,600% of our daily need.

Is That Much Vitamin A Bad?

Not all vitamins, particularly fat-soluble ones, should be eaten in large quantity. A huge excess of Vitamin A is not good. Polar bear and seal liver, for example, are two types of liver we should all avoid. Both are excessively rich in Vitamin A. Consuming polar bear or seal liver can even result in death, according to research published back in 1942.

Vitamin A assumes a number of forms. One major form is Retinol. Image by NEUROtiker (modified).

Ahem! What About Fat and Cholesterol?

Liver contains a little over 3.5% fat. This level of fat is about one-fourth that of a typical cut of beef, according to the USDA’s calculations.

Triolein is an abundant fat found in olive oil. Image by National Institute of Standards and Technology (modified).

Fat molecules consist of three long-chain fatty acid molecules (molecules with a carboxylic acid group, -COOH) all attached to one short molecule of glycerin, losing three molecules of water in the process. See the image of triolein in this article for an example.

Does the reader put homemade gravy over his meat or mashed potatoes? Almost surely, he’s exceeded the fat level in liver. Moderation, then, and not elimination is the key.

Stick model of the cholesterol molecule. Image by BorisTM (modified).

Does the reader eat eggs? Two eggs contain more fat than 3.5 ounces of beef liver. How about cholesterol? Pound for pound, beef liver contains 10% less cholesterol than eggs.

Whether cholesterol is bad or not is left to the reader and his medical professional to decide. However, the reader is likely unaware that the cholesterol deposited in our bodies actually is produced by our body.

Should I Eat Fried Beef Liver?

So is liver good or bad for me? Should I eat it or should I not eat it? That depends on you, of course. Does your doctor tell you that you must severely control the fat or cholesterol in your diet? If not, have you ever tried liver?

No food is for everyone. Everyone has the right to eat what he chooses. But if you have never tried liver because you are prejudiced against it, why not give it a chance? It is one of the least expensive, most nutritious sources of animal protein out there. You might even prove to be one of those elite who can’t resist fried liver.

© Copyright 2016 Vincent Summers, All rights Reserved. Written For: Decoded Science
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Filed Under: Chemistry

Resources for this article

U.S. Department of Veteran Affairs. The Liver is a Filter. Accessed on December 15, 2016


University of California San Francisco. Cholesterol Content of Foods. Accessed on December 15, 2016


American Heart Association. About Cholesterol. Accessed on December 15, 2016


Harvard School of Public Health. Fats and Cholesterol. Accessed on December 15, 2016


B, Flávia, et al. Bioactive amines in fresh beef liver…. (2015). ScienceDirect. Accessed on December 15, 2016


H, HYO CHOL, et al. The natural polyamine spermine functions directly as a free radical scavenger. (1998). Proceeds of the National Academy of Science. Accessed on December 15, 2016


Cornell College. What processes does the liver undergo to remove toxins?. Accessed on December 15, 2016


Rodahl, K, et al. The Vitamin A Content and Toxicity of Bear and Seal Liver. (1942). Dunn Nutritional Laboratory, University of Cambridge, and Medical Research Council. Accessed on December 15, 2016


USDA. Ground Beef Calculator . Accessed on December 15, 2016




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Comments

  1. Gary Giberson says

    December 17, 2016 at 5:04 pm

    Hello Vince , I just want to say I thoroughly enjoyed your article.

    Reply
    • Vincent Summers says

      December 19, 2016 at 6:47 am

      Thank you, Gary. It’s good to hear from you. I think an article you might find quite interesting for obvious reasons is: https://www.decodedscience.org/chemistry-questions-organic-compounds-life-vitalism/52869

      Reply
  2. John A. Jaksich says

    December 15, 2016 at 7:04 pm

    Hi, Vincent- I think your article is outstanding. Enjoyed it throughout.

    Reply
    • Vincent Summers says

      December 15, 2016 at 7:15 pm

      I tip my hat to you, John. Thank you.

      Reply
      • John A. Jaksich says

        December 15, 2016 at 10:25 pm

        You are definitely welcome! 🙂

        Reply

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About the Author

Vincent Summers

Vincent Summers holds a Bachelor of Science in Chemistry, and worked for the National Radio Astronomy Observatory for 23 years. Vincent was involved in NASA’s extended Voyager2 program while there. Vincent has taken as many … Read Full Profile

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